Introduction: Decisions to withdraw or withhold curative or life-sustaining treatment can have a huge impact on the symptoms which the palliative-care team has to control. Palliative-care patients and their relatives may also turn to palliative-care physicians and nurses for advice regarding these treatments. We wanted to assess Indian palliative-care nurses and physicians’ attitudes towards withholding and withdrawal of curative or life-sustaining treatment. Method: From May to September 2008, we interviewed 14 physicians and 13 nurses working in different palliative-care programmes in (...) New Delhi, using a semi-structured questionnaire. For the interviews and analysis of the data we followed Grounded-Theory methodology. Results: Withholding a curative or life-sustaining treatment which may prolong a terminal cancer patient’s life with a few weeks but also has severe side-effects was generally considered acceptable by the interviewees. The majority of the interviewees agreed that life-sustaining treatments can be withdrawn in a patient who is in an irreversible coma. The palliative-care physicians and nurses were of the opinion that a patient has the right to refuse life-saving curative treatment. While reflecting upon the ethical acceptability of withholding or withdrawal of curative or life-sustaining treatment, the physicians and nurses were concerned about the whole patient and other people who may be affected by the decision. They were convinced they can play an important advisory role in the decision-making process. Conclusion: While deciding about the ethical issues, the physicians and nurses do not restrict their considerations to the physical aspects of the disease, but also reflect upon the complex wider consequences of the treatment decisions. (shrink)

Micro RNAs (miRNAs) have been shown to control many cellular processes including developmental timing in different organisms. The prediction that miRNAs are involved in regulating hox genes of flies and mouse is quite a recent idea and is supported by the finding that mir‐196 represses Hoxb8 gene expression. The non‐coding regions that encode these miRNAs are also conserved across species in the same way as other mechanisms that regulate expression of hox genes. On the contrary, until now no homeotic phenotype, (...) a hallmark of any hox gene mutation, had been associated with any hox miRNA. Recent work on bithorax complex miRNA (miR–iab‐4–5p) shows, for the first time, that miRNAs can lead to homeotic transformation. This miRNA regulates Ultrabithorax (Ubx) and results in the transformation of haltere to wing.1 This study unveils a new complexity and finesse to the regulation of hox gene expression pattern that is needed for determining the anteroposterior body axis in all bilaterians. BioEssays 28: 445–448, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

Section 1. Prologue -- section 2. The whole being -- section 3. Engaging with wholeness -- section 4. Wholeness in Kashmiri Shaivism -- section 5. The Buddhist perspective -- section 6. Wholeness in the modern world -- section 7. The workings of wholeness in our world -- section 8. Epilogue.

Spatially and temporally restricted expression of Hox genes requires multiple mechanisms at both the transcriptional and the post-transcriptional levels. New insight into this precise expression mechanism comes from recent findings of a novel sense–antisense miRNA combination from the bithorax complex of Drosophila melanogaster.1-4 These two miRNAs encoded from the same locus target 3′ untranslated regions of anterior hox genes, Antp, Ubx and abd-A to establish the dominance of posterior hox gene Abd-B in its expression domain. Such double-edge tools, sense–antisense miRNA (...) combinations, also operate at multiple loci in the genome implicating their wider impact on the post-transcriptional gene regulation in eukaryotes. BioEssays 30:1058–1061, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

On understand the Tantrism in light of the Tantrāloka of Abhinavagupta.

On the views of Paulo Freire, Brazilian educator on education; a study.

This paper attempts to explore the idea of mind on the basis of René Descartes and Gilbert Ryle’s vision. Descartes, a 17thcentury philosopher, developed a dualistic theory that posits the mind and body as distinct entities. According to him, the mind is an immaterial, non- extended entity with consciousness and rational thought, while the body is a material substance subject to physical laws. In contrast, 20th-century philosopher Ryle rejected the idea of a separate mental realm and argued for the unity (...) of mind and body. He criticized Cartesian dualism, proposing that mental states and mental processes are not separate from bodily behavior but are intricately intertwined with it. This comparative analysis delves into Descartes’s arguments for dualism, including the interaction between mind and body through the pineal gland and his ideas on the mind’s independence from the body. On the other hand, Ryle’s critique of dualism is examined, with a focus on his concept of “category mistake” and his advocacy for behaviorism, which prioritizes observable behavior over unobservable mental states. By exploring these two contrasting perspectives, this paper aims to comprehensively understand the historical development and implications of the notion of mind. It highlights the influence of Descartes’s dualistic framework on philosophical discourse and Ryle’s efforts to challenge it, emphasizing the importance of considering the relationship between mind, body, and behavior in understanding human cognition and experience. (shrink)

Contribution of emotional valence and arousal to attentional processing over time is not fully understood. We employed a rapid serial visual paradigm in three experiments to investigate the...

Avec plus de cent soixante mémorandums d’accords signés avec des constructeurs de barrages, l’Etat d’Arunashal Pradesh, situé dans l’Himalaya, dans une région nord-orientale de l’Inde faisant limite avec la Chine, le Boutant et le Myanmar, occupe une place de choix dans les plans d’aménagement hydroélectrique de l’Inde. Cet état est le foyer d’environ vingt-cinq communautés autochtones, chacune avec ses différentes traditions culturelles et institutionnelles pour l’administration des propriétés collectives, comme les terres agricoles et les forêts. À l’Arunachal Pradesh, à la (...) différence de nombreuses autres communautés de l’Inde, les droits de la communauté sur la terre et les forêts sont protégés par la loi. Malgré cela, avec le boom de l’énergie hydroélectrique, les contradictions entre les droits collectifs et les prérequis institutionnels du modèle de croissance néolibéral ont aiguisé les conflits dans cette région frontalière. (shrink)

Healthcare professionals such as nurses faced a tough time during the pandemic. Despite the personal and professional challenges, they contributed immensely during the pandemic. However, there were variations in nurses’ work engagement during the pandemic. One reason could be their personality, especially neuroticism. Neuroticism represents individuals’ proneness to distress in stressful situations, such as COVID-19. Hence, understanding how and in which conditions neuroticism influences work engagement is crucial. We used the Job Demand-Resource model to test the association between neuroticism and (...) work engagement. As neuroticism represents the stress-proneness of an individual, we further investigated if stress mediates the neuroticism-work engagement link. For the nurses, patient interaction is an integral part of their job. Based on the data collected from the nurses, we tested if contact with patients alleviates the adverse effect of neuroticism on work engagement. During COVID-19, there was an intense need for nursing support. Hence, avoiding duty when society is looking for support might induce a fear of stigmatization among the nurses. We examined if the perceived stigma of duty avoidance would affect the neuroticism-engagement relationship. Our results indicated that higher patient contact alleviated the adverse effect of neuroticism on work engagement. On the other hand, higher fear of stigma exacerbated the adverse effect of neuroticism on work engagement. We further checked the combined effect of beneficiary contact and fear of stigma on neuroticism-work engagement relationships. The findings highlighted the importance of societal factors and policymakers in enhancing nurses’ work engagement. (shrink)

While it is known that reward induces attentional prioritization, it is not clear what effect reward-learning has when associated with stimuli that are not fully perceived. The masked priming paradigm has been extensively used to investigate the indirect impact of brief stimuli on response behavior. Interestingly, the effect of masked primes is observed even when participants choose their responses freely. While classical theories assume this process to be automatic, recent studies have provided evidence for attentional modulations of masked priming effects. (...) Most such studies have manipulated bottom-up or top-down modes of attentional selection, but the role of “newer” forms of attentional control such as reward-learning and selection history remains unclear. In two experiments, with number and arrow primes, we examined whether reward-mediated attentional selection modulates masked priming when responses are chosen freely. In both experiments, we observed that primes associated with high-reward lead to enhanced free-choice priming compared to primes associated with no-reward. The effect was seen on both proportion of choices and response times, and was more evident in the faster responses. In the slower responses, the effect was diminished. Our study adds to the growing literature showing the susceptibility of masked priming to factors related to attention and executive control. (shrink)

In this modern world, a massive amount of data is processed and broadcasted daily. This includes the use of high energy, massive use of memory space, and increased power use. In a few applications, for example, image processing, signal processing, and possession of data signals, etc., the signals included can be viewed as light in a few spaces. The compressive sensing theory could be an appropriate contender to manage these limitations. “Compressive Sensing theory” preserves extremely helpful while signals are sparse (...) or compressible. It very well may be utilized to recoup light or compressive signals with less estimation than customary strategies. Two issues must be addressed by CS: plan of the estimation framework and advancement of a proficient sparse recovery calculation. The essential intention of this work expects to audit a few ideas and utilizations of compressive sensing and to give an overview of the most significant sparse recovery calculations from every class. The exhibition of acquisition and reconstruction strategies is examined regarding the Compression Ratio, Reconstruction Accuracy, Mean Square Error, and so on. (shrink)

Studies on small and medium enterprises or SMEs in India are scarce. What little is known shows that there is a need to know more about this sector, specially on their performance on responsible business practices. This paper reports the findings on the environmental awareness and practices of some Indian SMEs, from a study conducted by the present authors on 200 SMEs, in the manufacturing and service sectors, in the two Indian states of West Bengal and Odisha. The study results (...) show that environmentally responsible practices and the related concept of social responsibility of business are yet to take root at the Indian SME level. Some of the major findings reported are the lack of knowledge and interest about environmentally responsible business practices among the SME owner–managers, the perceived disconnect between environmental practices and socially responsible business practices, the total absence of reporting practices in the sector, and the disinterest in the 14001 certification. The study also mentions the perceived barriers and constraints reported by the SME owner–managers in the path of greater engagement with the environment. On the whole, the study concludes that there is an urgent need for sensitization, training, and mentoring the Indian SME owner–managers in order to develop their capabilities for improved environmentally responsible business practices. (shrink)

Since the conceptualization of unethical pro-organizational behavior ten years ago, scholarly interest in exploring this phenomenon has multiplied. Given a burgeoning body of empirical research, a review of unethical pro-organizational behavior literature is warranted. This study, therefore, systematically reviews the extant literature on unethical pro-organizational behavior and presents a comprehensive theory-based review of the past developments in this field. We classify previous studies based on their underlying theoretical perspectives and discuss the antecedents and consequences of unethical pro-organizational behavior in work (...) context. We also explicate the boundary conditions under which the influence of these antecedents gets accentuated or alleviated. Overall, this study synthesizes past knowledge to elucidate why, how, and when unethical pro-organizational behavior unfolds in the workplace. Finally, the gaps in the extant theorization are identified and an agenda for future research is proposed. (shrink)